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A PLATFORM TO AID SELECT THE OPTIMAL TOOL TO DESIGN GUIDE RNAS
《农业科学与工程前沿(英文)》 页码 296-305 doi: 10.15302/J-FASE-2022479
● Summaries on sgRNAs design.
Generation and repair of AID-initiated DNA lesions in B lymphocytes
null
《医学前沿(英文)》 2014年 第8卷 第2期 页码 201-216 doi: 10.1007/s11684-014-0324-4
Activation-induced deaminase (AID) initiates the secondary antibody diversification process in B lymphocytes. In mammalian B cells, this process includes somatic hypermutation (SHM) and class switch recombination (CSR), both of which require AID. AID induces U:G mismatch lesions in DNA that are subsequently converted into point mutations or DNA double stranded breaks during SHM/CSR. In a physiological context, AID targets immunoglobulin (Ig) loci to mediate SHM/CSR. However, recent studies reveal genome-wide access of AID to numerous non-Ig loci. Thus, AID poses a threat to the genome of B cells if AID-initiated DNA lesions cannot be properly repaired. In this review, we focus on the molecular mechanisms that regulate the specificity of AID targeting and the repair pathways responsible for processing AID-initiated DNA lesions.
关键词: class switch recombination somatic hypermutation activation-induced deaminase DNA repair genomic instability
Study on HCl removal for medical waste pyrolysis and combustion using a TG-FTIR analyzer
Hongmei ZHU,Weiying CHEN,Xuguang JIANG,Jianhua YAN,Yong CHI
《环境科学与工程前沿(英文)》 2015年 第9卷 第2期 页码 230-239 doi: 10.1007/s11783-014-0651-3
关键词: pollution medical waste pyrolysis combustion TG-FTIR HCl removal
Pyrolysis behaviors of oil sludge based on TG/FTIR and PY-GC/MS
Wei SONG, Jianguo LIU, Yongfeng NIE,
《环境科学与工程前沿(英文)》 2010年 第4卷 第1期 页码 59-64 doi: 10.1007/s11783-009-0152-y
关键词: oil sludge pyrolysis Thermogravimetric Analysis-Fourier Transform Infrared Spectroscopy (TG-FTIR) Pyrolysis-Gas Chromatography/Mass Spectrometry (PY-GC/MS)
null
《医学前沿(英文)》 2017年 第11卷 第3期 页码 432-439 doi: 10.1007/s11684-017-0511-1
Traditional Chinese patent medicines are widely used to treat stroke because it has good efficacy in the clinical environment. However, because of the lack of knowledge on traditional Chinese patent medicines, many Western physicians, who are accountable for the majority of clinical prescriptions for such medicine, are confused with the use of traditional Chinese patent medicines. Therefore, the aid-decision method is critical and necessary to help Western physicians rationally use traditional Chinese patent medicines. In this paper, Manifold Ranking is employed to develop the aid-decision model of traditional Chinese patent medicines for stroke treatment. First, 115 stroke patients from three hospitals are recruited in the cross-sectional survey. Simultaneously, traditional Chinese physicians determine the traditional Chinese patent medicines appropriate for each patient. Second, particular indicators are explored to characterize the population feature of traditional Chinese patent medicines for stroke treatment. Moreover, these particular indicators can be easily obtained by Western physicians and are feasible for widespread clinical application in the future. Third, the aid-decision model of traditional Chinese patent medicines for stroke treatment is constructed based on Manifold Ranking. Experimental results reveal that traditional Chinese patent medicines can be differentiated. Moreover, the proposed model can obtain high accuracy of aid decision.
关键词: traditional Chinese patent medicines stroke aid decision data mining manifold ranking
Estimation of photolysis half-lives of dyes in a continuous-flow system with the aid of quantitative
Davoud BEIKNEJAD,Mohammad Javad CHAICHI
《环境科学与工程前沿(英文)》 2014年 第8卷 第5期 页码 683-692 doi: 10.1007/s11783-014-0680-y
关键词: dye photolysis half-life quantitative structure-property relationship continuous-flow stepwise multiple linear regression partial least squares
范洪刚,顾菁,王亚琢,袁浩然,何明阳,孙富安
《中国工程科学》 2018年 第20卷 第3期 页码 102-108 doi: 10.15302/J-SSCAE-2018.03.015
为了探索生物质主要组分在与塑料共热解过程中的协同效应和小分子气体产物的变化规律,笔者采用热重-质谱联用(TG-MS)技术研究纤维素、木聚糖共热解样品的混合比例为1∶1(w/w),TG实验得到了各单组分以及混合组分的失重区间,通过对单组分TG数据的拟合得到理论值与实验值,比较得到混合组分在共热解过程中存在协同效应,可促进样品的分解。
Investigations on dehydration processes of trisodium citrate hydrates
Junyan GAO, Yanlei WANG, Hongxun HAO
《化学科学与工程前沿(英文)》 2012年 第6卷 第3期 页码 276-281 doi: 10.1007/s11705-012-1206-4
Research on combustion characteristics of bio-oil from sewage sludge
Rui LI, Baosheng JIN, Xiangru JIA, Zhaoping ZHONG, Gang XIAO, Xufeng FU
《化学科学与工程前沿(英文)》 2009年 第3卷 第2期 页码 161-166 doi: 10.1007/s11705-009-0057-0
关键词: bio-oil from sewage sludge fast pyrolysis combustion characteristics TG-FT-IR kinetic
Russian school of the theory and geometry of gearing: Its origin and golden period (1935 --1975)
Dmitry BABICHEV,Sergey LAGUTIN,Natalya BARMINA
《机械工程前沿(英文)》 2016年 第11卷 第1期 页码 44-59 doi: 10.1007/s11465-015-0360-z
During the second half of the twentieth century, Soviet scientists were among the world leaders in the theory and geometry of gearing or the theoretical fundamentals of designing gears and gear-cutting tools. The authors of the current paper review works related to the development of the theory of gearing (TG) written in Russian from the mid-1930s to the present. Overall, the review covers more than 400 publications of nearly 200 authors (among more than 1000 studied works). This review involves some works on gear strength and accuracy to attract more experts.
This paper presents a short list of works from the seventeenth century to the nineteenth century and discusses the basic concepts of the TG. This paper also includes a review of more than 160 papers in Russian for the period of 1935–1975, which is the “golden age” of the TG. The main features and achievements during this period are also considered.
The distinctive feature of this review is the use of diagrams that visually present TG experts and the dates and themes of their published works. The diagrams also show the following aspects: 1) The most popular and important themes in a specific period, 2) the most important publications on the themes of interest to readers, and 3) the direction of the works and scope of interests of every researcher.
关键词: theory of gearing (TG) gear geometry generating surface gear synthesis gear analysis
WANG Shurong, LIU Qian, LUO Zhongyang, WEN Lihua, CEN Kefa
《能源前沿(英文)》 2007年 第1卷 第4期 页码 413-419 doi: 10.1007/s11708-007-0060-8
Yuheng FENG, Xuguang JIANG, Yong CHI, Xiaodong LI, Hongmei ZHU
《环境科学与工程前沿(英文)》 2011年 第5卷 第2期 页码 186-192 doi: 10.1007/s11783-011-0322-6
关键词: hazardous waste combustion pyrolysis thermogravimetric coupled with Fourier transform infrared analysis (TG-FTIR) monopotassium phosphate residue
汤广福 ,周静 ,庞辉 ,林俊杰 ,范征 ,吴亚楠 ,贺之渊 ,马士聪 ,薛峰 ,周保荣
《中国工程科学》 2023年 第25卷 第2期 页码 79-88 doi: 10.15302/J-SSCAE-2023.02.010
构建新型电力系统是实现碳达峰、碳中和战略目标,确保能源安全转型的关键路径;电力系统作为当前规模最大、层次复杂、强非线性的人造系统,是未来能源转型的核心,而新能源发电的波动性、随机性将使电力系统安全面临严峻挑战。本文结合我国能源安全转型面临的新形势、新挑战,明确了能源安全涉及的供给、环境、经济、科技等方面的内涵;探讨了能源转型的发展目标与战略路径,阐述了新型电力系统对于能源安全的重要性;剖析了影响新型电力系统安全发展的电源、电网、负荷、储能、市场、技术等关键环节。研究认为,需从应急预警、共享互济、安全防御3 个层面着手,构建新型电力系统安全发展所需的核心体系;进一步提出了新型电力系统发展路径研究的基本思路,以期为新型电力系统构建及安全发展研究提供基础参考。
标题 作者 时间 类型 操作
Study on HCl removal for medical waste pyrolysis and combustion using a TG-FTIR analyzer
Hongmei ZHU,Weiying CHEN,Xuguang JIANG,Jianhua YAN,Yong CHI
期刊论文
Pyrolysis behaviors of oil sludge based on TG/FTIR and PY-GC/MS
Wei SONG, Jianguo LIU, Yongfeng NIE,
期刊论文
A novel classification method for aid decision of traditional Chinese patent medicines for stroke treatment
null
期刊论文
Estimation of photolysis half-lives of dyes in a continuous-flow system with the aid of quantitative
Davoud BEIKNEJAD,Mohammad Javad CHAICHI
期刊论文
Investigations on dehydration processes of trisodium citrate hydrates
Junyan GAO, Yanlei WANG, Hongxun HAO
期刊论文
Research on combustion characteristics of bio-oil from sewage sludge
Rui LI, Baosheng JIN, Xiangru JIA, Zhaoping ZHONG, Gang XIAO, Xufeng FU
期刊论文
Russian school of the theory and geometry of gearing: Its origin and golden period (1935 --1975)
Dmitry BABICHEV,Sergey LAGUTIN,Natalya BARMINA
期刊论文
Mechanism study on cellulose pyrolysis using thermogravimetric analysis coupled with infrared spectroscopy
WANG Shurong, LIU Qian, LUO Zhongyang, WEN Lihua, CEN Kefa
期刊论文
Thermogravimetric coupled with Fourier transform infrared analysis study on thermal treatment of monopotassium phosphate residue
Yuheng FENG, Xuguang JIANG, Yong CHI, Xiaodong LI, Hongmei ZHU
期刊论文